Aquios CL
Improve handling of potentially biohazardous sample material through cap piercing
Increase productivity with high-throughput performance
Enable full traceability through barcoded reagents and LIS connectivity
Benefit from a Windows 10 operating system
The AQUIOS CL Flow Cytometer is a benchtop instrument capable of combining automated sample preparation and cellular analysis in a compact system. A 488 nm Solid State Diode Laser provides the light source for scatter and fluorescence measurements. Measurable parameters include Forward-Scatter (FS) and Electronic Volume (EV) for sizing, Side-Scatter (SS) for granularity measurements, and up to four independent fluorescence parameters. Easy to learn, easy to use, ideal for cross-training your lab staff, and represents a breakthrough solution to the most basic operational challenges of flow cytometry. With the Aquios CL you can minimize hands-on time with an integrated system that incorporates automated loading, sample preparation, reagent management, barcode scanning, data analysis, and full LIS connectivity. Minimizes exposure to potentially biohazardous material, such as open blood tubes. Aquios CL uses cap piercing technology, so you never have to deal with open blood tubes. The Aquios CL provides a 24/7 flow cytometry service, as the unit can be operated safely by minimally trained users. There’s minimize potential for user error inherent in systems that require numerous manual steps to set up and run. Accelerate your test turnaround time with high-throughput performance that eliminates many of the least efficient features of existing systems. Includes a computer-based onsite training system to get users up to speed quickly. The AQUIOS CL Flow Cytometer is intended for use with in vitro diagnostic flow cytometric applications using up to four fluorescent detection channels using a blue (488 nm) laser, two light scatter detection channels and electronic volume (EV).
Full Bidirectional LIS Connectivity
- Automatic retrieval of test requests and transmission of test results
- No need for additional workstations or software to connect to the LIS System
- No need to create or download worklists manually
Automated System Setup
- Preprogrammed protocols per application
- No daily setup reagents required
- No manual system or controls optimization
- Power on, system warmup, load controls, load samples – that’s it!
Smart Track Reagent Monitoring
- Uses a range of barcoded reagents and consumables
- Automatic barcode scanning to track those reagents, lot numbers, open and closed vial expiration dates, and number of tests or volume per reagent container
- Continuous tracking of reagent usage
- Automatic reagent monitoring including the number of tests remaining and warnings when reagents are low, out or expired
Cassette Autoloader
- Total capacity 40 sample tubes
- Accommodates a variety of tube sizes
- Continuous, random loading and unloading
- Separate single-tube loader for STAT samples, open vials, and tubes that are not barcoded
Automated Sample Preparation
- Automatic matching of sample identification code with the test request
- All sample preparation and analysis performed in 96-well microplates
- Automatic launch of applicable testing protocol
- Positive specimen ID and automatic specimen mixing immediately prior to aspiration
- Automatic dispensing and mixing of applicable reagents
- No manual pipetting of primary tubes
Pipeline Sample Processing*
- Eliminate slow, inefficient batch processing of samples
- 20 minutes to the first result after sample load (measured with Tetra-1 or Tetra-2+)
- After the first result, it’s 25 results/hour for up to one full 96-well plate (measured with Tetra Combo)
- Two multitasking probes: one for cap piercing and sample preparation, the other for aspirating prepared samples for analysis
- Each sample is analyzed as soon as it is ready
- Intelligent analysis algorithm sets all gates and regions automatically
- System flags samples that don’t meet autovalidation criteria
*patent pending
Real Time Sample Monitoring
- Intuitive software interface indicates the status of each sample
- Know at a glance where each sample is in the process and how much time until results are available
Comprehensive Quality Control
- Barcode tracking means no manual QC or reagent logs
- Generate a full, easily reviewable audit trail that includes reagent traceability
- Should QC fail, operator is alerted via text message or email
AQUIOS CL System Specifications:
Dimensions:
- System: W: 32” (82 cm); D: 22” (56 cm); H: 22” (56 cm)
- Workstation: W: 23” (59cm); D: 5” (13cm); H: 18” (46cm)
- Supply Cart: W: 21” (54cm); D: 18” (46cm); H: 16” (41cm)
Sample Loading: Autoloader holds up to 8 cassettes at a time with up to 5 sample tubes each and allows for continuous loading and unloading. A separate single-tube loader nables both open- and closed-vial sampling.
Automate Your Workflow
True load and go workflow automation on the AQUIOS CL allows you to run standardized IVD cleared assays for lymphocyte subset analysis and CD34+ stem cell enumeration. ADS 2.0 additionally allows the usage of customized reagents to automate user defined test.
AQUIOS Tetra Reagents
Fast, Efficient, High Throughput Lymphocyte Subset Analysis
In the clinical management of immune deficiency diseases, accurately counting the absolute cell numbers of leukocyte subsets and measuring the percentage of individual subtypes in blood is critical. The AQUIOS CL flow cytometer in combination with AQUIOS Tetra reagents provides a Single Platform Technology (SPT) for lymphocyte subset analysis and enumeration without the need for counting beads.
AQUIOS Tetra system tests for simultaneous identification and enumeration of T, B, and NK lymphocytes in whole blood are proven for reliability and precision.
AQUIOS Tetra Reagents
AQUIOS Tetra-1 and AQUIOS Tetra-2+ are for In Vitro Diagnostic Use. AQUIOS CL with Tetra-1 has been accepted for the World Health Organization list of prequalified in vitro diagnostic products.
Barcoded Reagents
The AQUIOS reagents use a unique barcode identity for tracking reagent type, lot number, container number, expiration dates, and remaining reagent levels. The reagent consumption is monitored by the system as the samples are processed.
Comprehensive Quality Control
Barcode tracking eliminates the need for manual QC or reagent logs and generates a full, easily reviewable audit trail. Should QC fail, operator is alerted via text message or email.
Eliminate Steps with Every Sample
The AQUIOS CL System streamlines operations by incorporating automated loading, sample preparation, reagent management, and barcode scanning as well as data analysis and bidirectional LIS connectivity in one compact platform.
