Gyógyszerkutatás
These bioluminescent assays cover the following topics: ADME, apoptosis, cell viability, cytotoxicity, oxidative stress, GPCR's, histone deacetylation, metabolism, nuclear receptor pathways, proteases, kinases.
ADME Assays
Our wide selection of bioluminescent enzyme substrates for proteases and metabolic enzymes such as CYPs and MAO, among others, provide powerful tools for the ADME-Tox screen.
Apoptosis Assays
Get more data in less time when you multiplex cell health biomarkers. Measure one or multiple biomarkers in vitro or in situ to detect early or late events of apoptosis and get a quick status update on targeted cells.
Cell Viability Assays
Cell viability assay kits for easy measurement of viability in cell culture, 3D microtissues, bacterial cultures and virus-infected cells. Simple "add-mix-measure" protocols and convenient luminescent readout allow you to easily compare cell viability data from well-to-well, from plate-to-plate and from day-to-day.
Custom Assay Materials
Research-grade materials based on luciferase reporter systems and HaloTag® technology. Includes NanoBRET™ technology for protein interaction detection.
Cytotoxicity Assays
Promega offers multiple readouts for quantifying cytotoxicity, including luminescent and fluorescent assays that can be multiplexed with apoptosis or viability assays to help determine mechanism of cell death.
Oxidative Stress Assays
Promega offers assays for detecting glutathione, measuring the ratio of reduced to oxidized glutathione and detecting changes in ROS as an indicator of cell health or cell signaling events.
GPCR Assays
Obtain better dynamic range and more biologically relevant data with the easy-to-use GloSensor™ assay format for live cell analysis.
Histone Deacetylase Assays
Simple, "add-mix-measure" luminescent assays for detecting HDAC and Sirtuin enzyme activities.
Metabolism Assays
NAD+, NADP+, NADH and NADPH are important cofactors for many enzymes involved in key cellular pathways, and quantitation of these dinucleotides is a standard approach to monitor enzyme activity directly or indirectly. Promega offers a number of systems to detect and quantify these important molecules.
Nuclear Receptor Pathway Tools
Follow nuclear receptor pathways with tools ranging from specific expression vectors to cell lines engineered to express your receptor of interest.
Protease Assays
Bioluminescent, homogeneous protease assays provide rapid, simple and sensitive measurement of protease activities directly from the cellular environment. Maximum sensitivity can be reached within 10–30 minutes of reagent addition, making these assays ideal for HTS applications.
Kinase Assays
Count on minimal interference from screening your compound library with luminescent, ATP-based kinase assays. These sensitive and reliable assays are easily scaled to meet your throughput needs.
