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Molecular Devices

GenePix 4300/4400 Microarray Scanner

GenePix 4300/4400 Microarray Scanner
The GenePix® 4300A and GenePix® 4400A Scanners from Molecular Devices offer maximum imaging quality with optimal resolution in highly configurable platforms. Configurations include 5μm or 2.5μm per-pixel maximum scanning resolution, choices of up to four lasers for excitation, and sixteen emission-wavelength filters. These options allow the systems to detect a wide variety of fluorophores. Coupled with GenePix® Pro Microarray Image Analysis Software and Acuity® Microarray Informatics Software, the GenePix Systems provide powerful, flexible, and easy-to-use solutions for the acquisition and analysis of data from all types of arrays, including nucleic acids, proteins, tissues, and cells.

 

High-resolution for High-density Microarrays:

  • Upgrade for the Future: While the GenePix® 4300A Microarray Scanner has a maximum resolution of 5µm per pixel; it can be upgraded to 2.5 micron per pixel resolution at any time. So you have the option to match the scanner resolution as your microarray research requirements advance.
  • Full Flexibility in Choosing Dyes: With up to four internal solid-state diode and gas lasers, the scanner is a remarkably compact bench-top unit. The laser flexibility and choice of up to 12 user-accessible emission filters allow you to select your dyes from a broad variety of fluorophores for your assay (CyTM3 and CyTM5 dyes, Fluorescein, GFP, Texas Red, Alexa Fluor® dyes, or quantum dots.
  • Trust your Microarray Signals: with outstanding positional performance and uniformity, the GenePix® 4300 and 4400 Microarray Scanners allow you to perform the most demanding application, like latest generation NimbleGen® arrays or array CGH experiments. Specified and tested for a field uniformity of +/- 2%, these scanners resolve a spatial frequency of 200 line pairs per millimeter (LPPM), and feature a contrast ratio (CTF) of least 50% at the highest resolution.
  • Less Noise in Your Data: Get unparalleled signal-to-noise (SNR) performance. GenePix® Microarray Scanners uses only the best components, like low-noise digitizer and photomultiplier tube (PMT), highest quality optical filters and sensors to reduce scattered light. Together these improvements reduce the noise to a minimum and increase the sensitivity. Unparalleled sensitivity also enables the use of lower laser power settings, which significantly reduces any perceived degradation of your dyes.
  • Less Breakable Components: Your microarray is safe in our scanner. With the newly designed six-point-slide holder, we exclusively rely on high-precision machining to eliminate fallible components as commonly used in dynamic autofocus systems.
  • Designed for High Duty-Cycle Usage: Improved high duty-cycle motors ensure maximum translation and focus motor lifetime. The new patent pending voice coil was designed to minimize vibration and optimize heat dissipation.
  • The GenePix 4400A Microarray Scanner is capable of scanning at a user-defined optical pixel resolution between 2.5 and 100 micron per pixel - allowing you to scan the highest-density microarrays on the market.

The GenePix® 4300/4400 Microarray Scanner and GenePix® Pro Microarray Analysis Software have been designed to work together as a complete, integrated platform. The seamless communication between scanner and software ensures unmatched efficiency for data acquisition and analysis, as well as for real-time scanner performance monitoring. Optional Acuity® Microarray Informatics Software completes the package, offering database storage, clustering algorithms, advanced statistics and visualizations.

 

The GenePix 4300/4400 Microarray Scanners are compatible with the following:
 
  • GenePix® SL50 Automated Slide Loader
  • GenePix® Pro 7 Acquisition and Analysis Software
  • Standard microscope slides (1" x 3", 25 x 75 mm; 0.9-1.1 mm thick)