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Molecular Devices

FLIPR Tetra High-Throughput Cellular Screening System

FLIPR Tetra High-Throughput Cellular Screening System
Industry-renowned, flexible, and reliable real-time kinetic cellular assay screening system for identifying early leads against GPCR and ion channel receptors

Quickly transform your creative concepts into real-time kinetic cellular assays for identifying early leads against GPCRs and ion channel targets. Our FLIPR Tetra® High-Throughput Cellular Screening System is fast, reliable, and remarkably easy to configure. The system is optimized for use with both fluorescence and luminescence, and adapts readily to your assay format with user-changeable 96-, 384-, and 1536-well heads.
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Transform your ideas into fast, effective, cellular screening assays    

  • Configure and switch between fluorescence or luminescence read modes for assay flexibility
  • Multiple read modes support both single wavelength and ratiometric assays
  • Choice of fluorescent or dual-mode cameras (FL and LUM) for increased assay flexibility
  • User-changeable 96-, 384-, and 1536-pipettor heads easily change assay formats depending on your throughput needs
  • Configurable pipettor height and dispense speeds ensure proper mixing without disturbing cell monolayers or non-adherent cells
  • User-configurable optics supports rapid optic changes in a multi-user, multi-assay environment
  • Drag-and-drop software interface easily builds multiple step protocols for easy protocol definition
  • User-defined protocols can include up to four wash solvents to automate cleaning of cell handling system
  • Configurable data export in either time-sequence or well-based format of single or multiple data files enables analysis by Microsoft Excel, Spotfire, or other analysis program

Take Advantage of These Great Features

  • Fluorescence camera enables use of homogeneous FLIPR calcium and membrane potential kits
  • Contact based elastomeric liquid transfer for 1536 pipettor provides accurate pipetting of compounds and cells
  • Simultaneous pipet and read function enables fast kinetic assays such as calcium flux in multiple wells
  • Cell suspension system with adjustable stirring speed, pump, and pipetting parameters facilitates optimization with different cell types
  • Cell suspension system eliminates the need for separate compound plate during Aequorin assays
  • FLIPR TetraCycler Plate Handler enables microplate and pipette tip changes and facilitates integration to laboratory robotics systems
  • Software displays only options relevant to the instrument configuration and eliminates the opportunity to make protocol errors
  • User-defined protocols can include up to four wash solvents to automate cleaning of cell handling system
  • Viewing signal traces, EC50 curves, and Z factors on the fly provides quick data analysis without having to export data to another software program

Assay Kits

  • We offer a full line of assay kits optimized for use with the FLIPR Tetra System.