Cell signaling
Here you can find everything you may ever need for signaling studies: AMP detection, GPCR assays, histone deacetylase assays, kinase resources and tools for nuclear receptor and protein phosphatase studies.
AMP Detection System
The AMP-Glo™ Assay is a homogeneous assay that generates a luminescent signal from any biochemical reaction that produces AMP. This versatile system can measure the activity of a broad range of enzymes.
GPCR Assays
Obtain better dynamic range and more biologically relevant data with the easy-to-use GloSensor™ assay format for live cell analysis.
Live-Cell Biosensor for GPCR Studies
Obtain data directly from living cells with the GloSensor™ cAMP Assay is a 'zero step' assay for studies on cAMP kinetics.
Custom Assay Services
Let us partner with you to develop a complete biology-driven, Promega-technology-enabled custom solution: Faster time to data; Fewer in-house resources; Flexible approach and offerings.
cAMP-Glo™ Assay
The cAMP-Glo™ Assay is a bioluminescence assay for monitoring changes in intracellular cAMP concentration with high sensitivity and excellent reproducibility. The assay is robust, easy to use and can be formatted to any size of experiment from single tubes to high-density plates.
Protein Kinases
We offer several protein kinases and kinase catalytic subunits including PKA, PKC, DNA- PK, Casein Kinase I and II, the EGF receptor and cGMP-dependent PK.
GTPase-Glo™ Assay
Measure intrinsic GTPase, GAP and GEF activity with the GTPase-Glo™ Assay. The amount of bioluminescence produced is inversely correlated to GTPase, GAP and GEF activity.
Growth Factors
Achieve consistent biological responses with highly purified, recombinant growth factors.
Histone Deacetylase Assays
Simple, "add-mix-measure" luminescent assays for detecting HDAC and Sirtuin enzyme activities.
Kinase Assays
Count on minimal interference from screening your compound library with luminescent, ATP-based kinase assays. These sensitive and reliable assays are easily scaled to meet your throughput needs.
Nuclear Receptor Pathway Tools
Follow nuclear receptor pathways with tools ranging from specific expression vectors to cell lines engineered to express your receptor of interest.
Protein Phosphatase Assays
Expect more from non-radioactive phosphatase assays that provide the high level of sensitvity and reliability (Z´-factor > 0.7) required for your high-throughput screening
